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drugs No.5985

Have you ever used drugs, or do you use them currently? I just ordered DXM.

No.5986

I rarely drink.

No.5990

No, but I wanna. How do I get drugs?

No.5991

>>4027
Drug thread also.

No.5992

>>5991
Damn I didn’t know, sorry

No.5997

I'm trying to rid my life of beer and coffee, but I can't say no when I'm offered.
Wish I lived on my own, then I wouldn't have any garbage in my home. I'm trapped with these degenerate niggers that drink "shots" and smoke and curse and have sex.
I don't know why God put me with these retarded faggot niggers.

No.6005

>>5992
I don't care, just thought the content might interest you.

>>5997
I managed to rid my life of alcohol and drugs, but not caffeine. I can temporarily, but even when the tolerance and dependence is gone I just... Know it's refreshing for my mind.

No.6007

Take the white pill: https://robocough.com/

It seriously is a different experience from chugging Robitussin.

You can also buy delta8 legally online or at your local headship. Delta8, unlike CBD, actually does get you fucked up. You can thank Trump for making it federally legal!

No.6030

I like stimulants and opioids

No.6032

>>6030
What specifically? It seems most of the heroin fans I've met don't like doing meth and vice-versa. I've never met anyone who actually enjoys speedballs. They cancel each other out and you just feel fucked up rather than high

No.6075

delta 8 sucks. does not get me high at all.

No.6078

>>6075
How sketchy was the brand? These guys are the most expensive, but I've never heard any complaints from people I recommended them to: https://www.3chi.com/

No.6091

>>6032
Mostly pharmaceuticals and occasionally over the counter shit (benzedrex). Oxycodone, hydrocodone, amphetamines, benzedrex. I've tried meth and heroin a few times but thankfully got away from those bad influences before I became addicted. I've rarely mixed them but I do love the feeling of a speedball or 'pharmball' though, it sounds like it would cancel each other out but it really synergizes very well in my experience.

No.6122

OP here, just took a full bottle of robocough about an hour ago. It’s not fun tbh, I feel dizzy and it’s hard for me to focus on stuff. So far is hasn’t been very fun. Worried I might have a panic attack. This is my first time taking DXM

In addition, the liquid robocough tastes like ass, I gagged multiple times.

No.6125

>>6122
OP here again, I just threw ip

No.6127

Pease help me I do that to have a panic attack

No.6128

I’m tripping

No.6130

Op here, I feel ok now, I think I was just freaked out by the come up.

No.6131

I don’t think I’m going to do this again.

No.6132

>>6122
>>6127
>>6130
>>6131
Panic attacks suck ass. I quit using drugs forever because of them.

No.6134

>>6132
I just don’t get how this is supposed to fun. I’m tripping and all I’m experiencing is dizziness, nausea and anxiety. There was a brief moment where I hallucinated something on the television, that was cool.

No.6137

>>6134
Actually I didn’t hallucinate anything lol

No.6142

OP here. Now since it’s worn off, I can say that, although it was interesting, I don’t think DXM is for me. I threw away my remaining RoboCough bottles.

No.6143

>>6142
Let this thread stand as a warning to impressionable young neets then - don't take dxm.

No.6145

>>6143
it's just comical how there is an entire subreddit dedicated to it with people saying how good it makes them feel and my experience was literally 100% bad

No.6148

>>6134
You lack the sacred CYPD26 enzyme required to enjoy DXM: https://pubmed.ncbi.nlm.nih.gov/9690700/

Only about 1 in 3 people have sufficient quantities of this enzyme to get the pleasureable effects. The rule of thumb is a third of people love dxm, a third had your neutral experience, and a third exclusively have bad trips on it. At least you know now!

No.6149

>>6145
It really is good if you don't lack the enzyme. It sounds like it's not for you but I encourage other NEETs to try it for themselves. Give William Whites in-depth DXM FAQ a read too: https://erowid.org/chemicals/dxm/faq/dxm_faq.shtml

No.6152

I don't use drugs except tobacco.

No.6155

Am I the only neet who never tried drugs because he didn't have any friends to introduce him to them?

No.6156

>>6148
>the sacred CYPD26 enzyme required to enjoy DXM
This sounds like a cope, but I’m not a biologist so I have no way to prove you wrong.

I will say that the negative effects of my trip were almost entirely limited to the “come up”, and once that finished it was tolerable, but it took almost 2 hours to get to that point and I was all but shitting bricks the whole time. If I could theoretically avoid the come up it might be worth it to try it again. Many people in the dxm subreddit complain about the come up.

No.6157

I used prescription benzos and ADHD stims for many years, and wish to god I hadn't. Also have a long history of binge eating sugary to try and affect my mood or because I was addicted to sugar rush. This would be described as substance abuse if it were anything else but food.

No.6161

>>6155
Get some Bitcoin and learn to use dark.fail or get some USD and but roboxough or delta8 online

>>6156
1) I provided a scientific journal article source for my claim about the CYPD26 enzyme
2) there are clearly tons of other people online who enjoy DXM
3) the robocough guys created a profitable business off people enjoying the DXM high

Sounds like the guy who lacks the ability to trip balls legally is the one coping. Seriously, check out the DXM FAQ, most people lack the ability to enjoy DXM and we weep for them: https://erowid.org/chemicals/dxm/faq/dxm_general_info.shtml#toc.4.7

If it makes you feel any better, I personally lack the ability to enjoy opiates. I don't get any pleasurable feelings from them, it's just nausea until I fall asleep.

No.6162

>>6157
Sugar is absolutely a drug. It's an addictive white powder that makes you feel good but comes with a physiological cost

No.6163

>>6161
There's also people who can't process Codeine into Morphine. Also some people who get really strong effects from it and are at risk of overdose from what most users would call meh for a new user. Not me though, for me it's really fucking strong. I avoid opiates though, too addictive.
https://medsafe.govt.nz/profs/PUArticles/June2018/SpotlightOnCodeine.htm
Appears to be the same enzyme causing variation as with DXM. I never tried DXM though.

No.6170

>>6161
>I'm right because this single study says so
Yeah I'm sure

No.6185

>>6161
You didn’t even address my core point

No.6188

>>6170
Anon literally gives you proof and you dismiss it. It's a rather well known fact.

No.6192
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>>6185
what's your core point? that you feel like you wasted money? well, that sucks bro, but at least you now possess the knowledge that you specifically are unable to enjoy DXM. why not try reading the DXM FAQ? https://erowid.org/chemicals/dxm/faq/dxm_general_info.shtml#toc.4.7

>>4.7 Does Everyone Like DXM?
>No, in fact from speaking with many people who have tried it, only about one third of the people who try it ever take it again. One third seem to absolutely hate it, and the last third couldn't care less. Among the third who do like it, the majority (around 80% of those who like DXM) take it once a month or less.
>Part of the problem is that not everyone gets the interesting sets of effects (see Section 5). To some, the DXM trip is just a moderate buzzing sensation and a feeling of being slightly drunk. So your mileage may vary.
>A few people really enjoy DXM, and use it weekly; a very few (less than 5% of those who like DXM) use it more than twice a week. Keep in mind that I have not assessed the error margin on these figures, and that they reflect a biased sample of the population. I hope to have more accurate figures after completing a survey of DXM users.

>>5.15 Why does DXM Affect Different People So Differently?
>Several reasons. First off, there is a liver enzyme known as cytochrome P450-2D6 (also CYP2D6, or debrisoquine 4-hydroxylase), which metabolizes DXM. Some people lack this enzyme, and of those who have it, subtle genetic variations can result in different activity (10-18). Thus, while one person may metabolize DXM quickly, another may not (there are other pathways which are much slower). Certain drugs - such as fluoxetine (ProzacTM) can inhibit this enzyme (39). A partial list of P450-2D6 inhibiting drugs is given in Section 15.1.
>Second, some of the effects of DXM are due to the DXM itself, and some are due to its metabolite dextrorphan (DXO), which is more similar to PCP and ketamine in its neuroreceptor activity (43). Some individuals may metabolize high doses of dextromethorphan to dextrorphan more quickly than others. Incidentally, my opinion - based on anecdotal evidence of recreational DXM use while on fluoxetine - is that both DXM and dextorphan are responsible for the psychoactive effects (yes, I changed my mind). There is evidence to show that DXM is definitely involved, and may be responsible for most of the lower plateau effects (32).
>Third, NMDA receptors are intimately involved in many areas of the brain where a great deal of processing takes place, such as the hippocampus and the cerebellum. In contrast to the biogenic amine neurotransmitters (serotonin, dopamine, noradrenaline, histamine, and acetylcholine) which seem to play a modulatory role, excitatory amino acids and NMDA receptors are involved in the "nitty gritty" of brain processes. It is possible that, due to this extensive involvement, many different cortical and limbic circuits may be affected.
>In fact, DXM affects at least four different binding sites (see Section 9.2), and each of these is subject to subtle variance from person to person (44).
>A few people have suggested that temporal lobe epilepsy may greatly change the DXM experience (pers. comm.). If nothing else, it has been implicated in cognitive impairment from DXM use (136). Additionally, some of the more profound dissociative experiences (see Section 8.2.1) may be altered, and possibly amplified, by having an underlying susceptibility to seizures.
>There are probably a gazillion other reasons why DXM has such a wide range of effects. Subtle differences in brain chemistry, notably in terms of sigma receptors, may also be involved. Psychological set, as well as setting, are undoubtedly also part of the problem.


>>6188
I honestly would lash out at people too if I just learned my genetics prevent me from enjoying something. Having insufficient quantities of the CYPD26 enzyme is no different than having insufficient penis length to enjoy sex.

No.6193

>>6192
I told you that my experience mirrored what others on the DXM subreddit say they have experienced. The come up was shitty, and after that it felt better. The DXM Reddit community seems to think the come up is worth it because of what comes after, for me it’s not, but that’s just a difference of opinion.

You’re literally encouraging people to ingest what amounts to a neurotoxin just to get a shitty high.

No.6194

>>6193
It's not a shitty high for the chosen people who possess the sacred CYP2D6 enzyme. So you're not one of the chosen ones. Big whoop. Neither are most other people. Get over it.

No.6195

>>6194
>makes an unfalsifiable claim
>”get over it”
ok buddy

No.6196

Everyone has a drug of choice. So yours differ, whatever. Some people love MDMA, yet some people hate it. Some people love LSD, yet some people hate it. Some people love Opiates, yet some people hate them.
It's whatever, people feel different about different drugs. I for one can't stand alcohol or cocaine, lots of people love that stuff though. Personality traits, and just individual differences in bodies.

No.6198
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>>6196
Exactly. I'm pretty autistic and I've never understood getting mad at people who like different things.

No.6199

This anon here is on SSRI for almost 20 years, also gets pregabalin and a benzo for social situations like phonecalls. Anon also drinks and sometimes smokes.